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Natural Supplements for ADHD: Exploring Complementary Treatments

Natural Supplements for ADHD: Exploring Complementary Treatments


Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition characterised by inattention, hyperactivity, and impulsivity. While stimulant medications are often the first-line treatment for ADHD, many individuals and families seek out complementary and alternative approaches to manage symptoms. Natural supplements for ADHD have gained increasing attention in recent years as potential tools to support brain function and alleviate symptoms.

Exploring natural supplements as part of a comprehensive ADHD treatment plan is essential, as these substances may offer additional benefits and support overall well-being. However, it is crucial to approach the use of supplements with caution and under the guidance of a healthcare professional. Supplements can interact with medications and may cause side effects if not used appropriately. This article aims to provide an overview of the most promising natural supplements for ADHD based on current research, discuss their potential benefits and limitations, and emphasise the importance of working with a qualified practitioner to develop a personalised treatment plan.

Omega-3 Fatty Acids

Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been extensively studied for their potential benefits in managing ADHD symptoms. These essential fatty acids play a crucial role in brain development and function, and deficiencies have been linked to various mental health disorders, including ADHD (Parletta et al., 2016).

A comprehensive review by Naidoo (2017) analysed 16 studies investigating the effects of omega-3 and omega-6 fatty acid supplementation on ADHD symptoms in children and adolescents. The review concluded that these supplements might help improve attention, impulsivity, and hyperactivity, with omega-3 supplements being about 40% as effective as stimulant medication in reducing symptoms. The authors suggest that a combination of EPA and DHA may be most beneficial, with dosages ranging from 500 to 1,500 mg per day (Naidoo, 2017).

Food sources rich in omega-3 fatty acids include fatty fish like salmon and sardines, as well as flaxseeds, chia seeds, and walnuts. When considering omega-3 supplements, it is essential to choose high-quality brands that have been third-party tested for purity and potency. Consulting with a healthcare professional can help determine the appropriate dosage and ensure the supplement is safe for individual use.


Zinc is an essential mineral that plays a vital role in brain function and neurotransmitter synthesis. Several studies have found an association between low zinc levels and ADHD symptoms, suggesting that zinc deficiencies may contribute to the disorder (Robberecht et al., 2020).

However, the evidence on zinc supplementation’s efficacy in managing ADHD symptoms is mixed. A systematic review and meta-analysis by Ghoreishy et al. (2021) found a strong association between low zinc status and ADHD symptoms, but the authors note that more research is needed to establish the effectiveness of zinc supplementation as a treatment option.

While some studies have shown that zinc supplementation may help reduce hyperactivity and impulsivity in children with ADHD, others have found no significant effects (Bloch & Mulqueen, 2014). The ideal dosage and form of zinc supplementation for ADHD management remain unclear, and further research is necessary to draw definitive conclusions.


Iron deficiencies have been linked to ADHD symptoms, and some experts believe that supplementation could improve behaviour in affected children. A study by Konofal et al. (2008) investigated the effects of iron supplementation in non-anaemic children with low ferritin levels, a protein that stores iron. After 12 weeks of supplementation, the children showed significant improvements in ADHD symptoms compared to the placebo group.

However, it is crucial to note that high iron levels can be dangerous, and iron supplementation should only be considered after a thorough evaluation of an individual’s iron status. A blood test can help determine if an iron deficiency is present and guide appropriate treatment decisions. Supplementation should be monitored closely by a healthcare professional to avoid potential adverse effects.


Magnesium is an essential mineral that plays a role in neurotransmitter function and has been studied for its potential calming effects on individuals with ADHD. Some research suggests that magnesium deficiencies may be more common in children with ADHD, and supplementation could help alleviate symptoms (Effatpanah et al., 2019).

A randomised controlled trial by Hemamy et al. (2021) investigated the effects of magnesium and vitamin D supplementation on the mental health status of children with ADHD. The study involved 66 children and found that the combination of magnesium and vitamin D significantly reduced emotional problems and relationship challenges compared to the placebo group. However, the authors note that more research is needed to confirm these benefits and determine the optimal dosage and duration of supplementation.

While magnesium supplements are generally well-tolerated, they can cause side effects such as diarrhoea and stomach discomfort in some individuals. It is essential to consult with a healthcare professional before starting magnesium supplementation to ensure safety and appropriate dosing.

Vitamin C

Vitamin C is a potent antioxidant that plays a role in modulating the neurotransmitter dopamine in the brain. Some experts, like Dr Ned Hallowell, suggest that a daily vitamin C supplement may be beneficial for children with ADHD, particularly if their diet is lacking in this essential nutrient (Naidoo, 2017).

However, it is important to note that vitamin C should not be taken within an hour of ADHD medication, as it may interfere with the absorption and effectiveness of the medication. Additionally, while vitamin C supplements are generally safe, high doses can cause side effects such as diarrhoea and stomach cramps.

Prioritising vitamin C-rich foods in the diet, such as citrus fruits, berries, and leafy greens, is a safe and effective way to ensure adequate intake. If supplementation is necessary, working with a healthcare professional can help determine the appropriate dosage and timing to avoid potential interactions with medications.


Polyphenols are plant-based compounds with potent antioxidant properties that may help restore neurological balance in individuals with ADHD. A study by Naidoo (2018) suggests that polyphenols could reduce oxidative damage in the brain, which may be more prevalent in individuals with ADHD.

Polyphenols are found in a variety of plant-based foods, including fruits, vegetables, nuts, and seeds. Some of the best sources include berries, cocoa, green tea, and red wine. While polyphenol supplements are available, obtaining these compounds through a balanced diet rich in plant-based foods is generally considered the safest and most effective approach.

More research is needed to fully understand the potential benefits of polyphenols for ADHD management and to determine the optimal intake levels for symptom improvement. However, incorporating polyphenol-rich foods into the diet may offer a range of health benefits beyond ADHD symptom management, making it a worthwhile consideration for overall well-being.


L-theanine is an amino acid found naturally in green tea that has been studied for its potential cognitive benefits, including improved attention and reduced mind wandering. A small study by Sadek et al. (2019) investigated the effects of L-theanine on cognition and mood in healthy children. The study involved five children and found potential benefits for attention span and overall cognitive performance.

While these initial findings are promising, larger and more robust studies are needed to confirm the effects of L-theanine on ADHD symptoms specifically. The optimal dosage and long-term safety of L-theanine supplementation for children with ADHD also require further investigation.

It is worth noting that L-theanine is generally well-tolerated and considered safe when consumed in moderate amounts, such as those found in green tea. However, as with any supplement, it is essential to consult with a healthcare professional before starting L-theanine supplementation to ensure safety and appropriate dosing, especially for children with ADHD who may be taking other medications.

Probiotics and Fermented Foods

The gut-brain connection has gained increasing attention in recent years, with emerging research suggesting that the gut microbiome may play a role in various mental health conditions, including ADHD. Probiotics and fermented foods have been studied for their potential to support a healthy gut microbiome and, in turn, promote better cognitive function and mental well-being.

A review by Naidoo (2019) highlights the link between gut health and brain function, suggesting that probiotics and fermented foods could be beneficial for ADHD management. The review discusses the potential mechanisms by which the gut microbiome may influence neurotransmitter production, inflammation, and other factors that impact brain health.

Fermented foods, such as yogurt, kefir, sauerkraut, and kimchi, are natural sources of beneficial probiotics. Incorporating these foods into the diet may help support a healthy gut microbiome and potentially offer benefits for ADHD symptoms. Probiotic supplements are also available, but it is essential to choose high-quality products and consult with a healthcare professional to ensure safety and appropriate use.

While the research on probiotics and fermented foods for ADHD management is still in its early stages, the potential benefits for overall brain health and well-being make them a promising area for further investigation. As with any dietary or supplement intervention, it is crucial to work with a qualified healthcare provider to develop a personalised plan that takes into account individual needs and potential interactions with other treatments.

Other Natural Approaches

In addition to natural supplements, several other complementary approaches may be beneficial for individuals with ADHD. These strategies can be used in conjunction with traditional treatments, such as medication and behavioural therapy, to support overall well-being and symptom management.

Nutrition and Diet

A balanced, nutrient-rich diet is essential for brain health and may play a role in managing ADHD symptoms. Some key dietary considerations for individuals with ADHD include:

  1. Emphasising complex carbohydrates, lean proteins, and healthy fats to provide steady energy and support neurotransmitter production (Stevenson et al., 2014).
  2. Minimising processed foods, added sugars, and artificial additives, which may exacerbate ADHD symptoms in some individuals (Nigg et al., 2012).
  3. Ensuring adequate intake of essential vitamins and minerals, such as iron, zinc, and magnesium, through a balanced diet or targeted supplementation under the guidance of a healthcare professional (Robberecht et al., 2020).

Working with a registered dietitian or nutritionist can help individuals with ADHD develop a personalised meal plan that meets their unique needs and preferences while supporting overall brain health.

Exercise and Physical Activity

Regular physical activity has been shown to have numerous benefits for individuals with ADHD, including improved focus, reduced hyperactivity, and better overall well-being (Cerrillo-Urbina et al., 2015). Engaging in exercise and physical activity can help:

  1. Increase dopamine and norepinephrine levels in the brain, which are important for attention and impulse control (Wigal et al., 2013).
  2. Reduce stress and anxiety, which can exacerbate ADHD symptoms (Stubbs et al., 2017).
  3. Improve sleep quality, which is essential for cognitive function and emotional regulation (Hvolby, 2015).

Encouraging individuals with ADHD to find physical activities they enjoy, such as team sports, dancing, or outdoor adventures, can help make exercise a sustainable and enjoyable part of their routine. Mind-body practices, such as yoga and tai chi, may also be beneficial for promoting relaxation and reducing stress (Herbert & Esparham, 2017).

Behavioural Therapy and Coping Strategies

Behavioural therapy is a key component of ADHD treatment and can help individuals develop coping strategies and organisational skills to better manage their symptoms. Some effective behavioural interventions for ADHD include:

  1. Cognitive-behavioural therapy (CBT), which helps individuals identify and change negative thought patterns and behaviours that contribute to ADHD symptoms (Young et al., 2020).
  2. Parent training programs, which teach caregivers strategies for managing ADHD symptoms and promoting positive behaviours in children (Daley et al., 2018).
  3. Organisational skills training, which helps individuals develop strategies for time management, task prioritisation, and goal setting (Bikic et al., 2017).

Working with a qualified mental health professional, such as a psychologist or licensed therapist, can help individuals with ADHD develop a personalised treatment plan that incorporates behavioural interventions and coping strategies tailored to their unique needs and challenges.

Precautions and Considerations

While natural supplements and complementary approaches may offer potential benefits for individuals with ADHD, it is essential to approach their use with caution and under the guidance of a qualified healthcare professional. Some important precautions and considerations include:

  1. Potential interactions between supplements and medications: Some natural supplements may interact with ADHD medications or other prescription drugs, leading to adverse effects or reduced effectiveness (Rao et al., 2018). It is crucial to disclose all supplements and medications to a healthcare provider to ensure safety and avoid potential interactions.

  2. Quality and purity of supplements: The supplement industry is not as strictly regulated as the pharmaceutical industry, which means that the quality and purity of supplements can vary widely (Starr, 2015). Choosing high-quality supplements from reputable brands and looking for third-party testing certifications can help ensure safety and potency.

  3. Individual differences in response: Not all individuals with ADHD will respond to natural supplements or complementary approaches in the same way. Some may experience significant benefits, while others may see little or no improvement in symptoms (Sarris et al., 2011). Working closely with a healthcare professional can help monitor progress and adjust treatment plans as needed.

  4. Importance of a comprehensive treatment approach: Natural supplements and complementary therapies should not be used as a sole treatment for ADHD but rather as part of a comprehensive treatment plan that may include medication, behavioural therapy, and lifestyle modifications (Catalá-López et al., 2017). Collaborating with a multidisciplinary team of healthcare professionals can help ensure that all aspects of ADHD management are addressed.


In conclusion, natural supplements and complementary approaches offer promising potential for supporting individuals with ADHD in managing their symptoms and improving overall well-being. While stimulant medications remain the first-line treatment for ADHD, exploring natural options can provide additional benefits and help address the unique needs of each individual.

The most promising natural supplements for ADHD, based on current research, include omega-3 fatty acids, zinc, iron, magnesium, vitamin C, polyphenols, L-theanine, and probiotics. These substances have been shown to support brain function, neurotransmitter balance, and cognitive performance in various studies. However, it is essential to note that the evidence for their efficacy in treating ADHD specifically is mixed, and more research is needed to establish clear guidelines for their use.

In addition to natural supplements, lifestyle factors such as nutrition, exercise, and behavioural therapy play a crucial role in ADHD management. Adopting a balanced, nutrient-rich diet, engaging in regular physical activity, and developing coping strategies through behavioural interventions can significantly improve symptoms and overall quality of life for individuals with ADHD.

It is crucial to approach the use of natural supplements and complementary therapies with caution and under the guidance of a qualified healthcare professional. Supplements can interact with medications and may cause adverse effects if not used appropriately. Working closely with a healthcare provider to develop a personalised, comprehensive treatment plan that considers individual needs, preferences, and potential risks is essential for safe and effective ADHD management.

As research continues to evolve, it is important to stay informed about the latest findings on natural supplements and complementary approaches for ADHD. By collaborating with healthcare professionals and exploring a range of treatment options, individuals with ADHD can find the right combination of strategies to support their unique needs and improve their overall well-being.

Key Highlights of Learnings and Actionable Tips

  • Natural supplements may be an alternative or addition to ADHD medication, but it’s important to check with your doctor first before trying any new supplements.
  • Supplements can offer targeted nutritional benefits and may help improve brain functioning and overall quality of life for people with ADHD.
  • When choosing supplements, look for high-quality products manufactured according to good manufacturing practices (GMP) by reputable brands. Discuss potential health risks and ideal dosage with a healthcare professional.
  • Polyphenols, vitamin C, zinc, iron, magnesium, omega-3 and omega-6 fats, L-theanine, fermented foods or probiotics, and melatonin are some of the best supplements that may help relieve ADHD symptoms.
  • Eating a nutritious diet rich in whole food sources of key nutrients is important. Supplements should complement, not replace, a healthy diet and lifestyle for ADHD management.

What other lifestyle factors can help manage ADHD alongside supplements?

In addition to taking supplements, several lifestyle factors can help manage ADHD symptoms:

  1. Regular exercise: Physical activity can improve focus, reduce hyperactivity and impulsivity, boost mood, and promote better sleep. Aim for at least 30-60 minutes of exercise most days of the week.

  2. Healthy sleep habits: Establishing a consistent sleep schedule and practicing good sleep hygiene can improve sleep quality and daytime functioning. Create a relaxing bedtime routine, avoid screens before bed, and aim for 7-9 hours of sleep per night.

  3. Stress management: Chronic stress can worsen ADHD symptoms. Engage in relaxation techniques like deep breathing, meditation, or yoga to help manage stress levels. Make time for hobbies and activities you enjoy.

  4. Structured routines: Having a consistent daily routine can help you stay organised and focused. Use calendars, to-do lists, and reminders to keep track of tasks and appointments. Break large projects into smaller, manageable steps.

  5. Supportive relationships: Surround yourself with supportive family and friends who understand your ADHD challenges. Consider joining a support group or working with a therapist who specialises in ADHD to develop coping strategies and improve relationships.

Are there any foods to avoid that may worsen ADHD symptoms?

Yes, certain foods and additives may exacerbate ADHD symptoms in some individuals:

  1. Refined sugars and simple carbohydrates: Foods high in added sugars and refined carbs can cause rapid spikes and crashes in blood sugar levels, which may lead to hyperactivity, irritability, and difficulty concentrating.

  2. Artificial food colours and preservatives: Some studies suggest that certain artificial food colours (like Red 40, Yellow 5, and Yellow 6) and preservatives (like sodium benzoate) may increase hyperactivity in children with ADHD.

  3. Caffeine: While some people with ADHD find that caffeine helps improve focus, others may experience increased anxiety, jitteriness, and sleep problems. Be mindful of your individual response to caffeine.

  4. Processed and junk foods: These foods often lack essential nutrients and are high in unhealthy fats, sugars, and additives that may negatively impact brain function and worsen ADHD symptoms.

It’s important to note that dietary triggers can vary from person to person. Keep a food diary to identify potential problem foods and discuss any dietary changes with a healthcare professional.

How long does it typically take to notice improvements in ADHD symptoms when taking supplements?

The time it takes to notice improvements in ADHD symptoms when taking supplements can vary depending on several factors, including:

  1. The specific supplement(s) being taken
  2. The individual’s unique brain chemistry and nutritional status
  3. The severity of ADHD symptoms
  4. Consistency in taking the supplements as directed

In general, it may take several weeks to a few months of consistent use to notice significant improvements in ADHD symptoms. Some people may experience mild benefits within a few days, while others may require more time.

It’s essential to be patient and not expect immediate results. Give the supplement regimen at least 1-3 months before evaluating its effectiveness. Keep track of any changes in symptoms, side effects, or overall well-being, and discuss your progress with a healthcare professional regularly.

Remember that supplements are not a quick fix and should be used in conjunction with other ADHD management strategies, such as therapy, medication (if prescribed), and lifestyle modifications, for optimal results.

Can supplements be used instead of prescription ADHD medications?

Supplements can be a helpful addition to an ADHD treatment plan, but they should not be used as a substitute for prescription medications without consulting a healthcare professional. While some individuals may find relief from ADHD symptoms through supplements alone, others may require medication for optimal management.

Prescription ADHD medications, such as stimulants (like methylphenidate or amphetamines) and non-stimulants (like atomoxetine or guanfacine), have been extensively studied and are proven to be effective in reducing ADHD symptoms for many people. These medications work by targeting specific neurotransmitters in the brain involved in attention, focus, and impulse control.

On the other hand, supplements aim to support overall brain health and function by providing essential nutrients that may be lacking. While some supplements have shown promise in reducing ADHD symptoms, the research is often limited, and results can be mixed.

It’s crucial to work closely with a healthcare professional to determine the best treatment approach for your individual needs. They can help you weigh the potential benefits and risks of supplements and medications, monitor your progress, and make adjustments as needed. Never stop taking prescribed ADHD medications or change your treatment plan without consulting your doctor first.

Are there any potential interactions between ADHD supplements and medications to be aware of?

Yes, there are potential interactions between ADHD supplements and medications that you should be aware of. Some supplements can interfere with the effectiveness of ADHD medications or cause adverse side effects when taken together. Here are a few examples:

  1. Iron supplements: Taking iron supplements along with methylphenidate (Ritalin) may decrease the absorption and effectiveness of the medication. Iron supplements should be taken at least 2 hours apart from methylphenidate.

  2. St. John’s Wort: This herbal supplement can interact with many medications, including ADHD drugs like atomoxetine (Strattera) and amphetamines (Adderall). St. John’s Wort may decrease the effectiveness of these medications and increase the risk of serotonin syndrome, a potentially dangerous condition.

  3. Omega-3 fatty acids: While generally safe, high doses of omega-3 supplements can increase the risk of bleeding, especially when taken with blood-thinning medications like aspirin or warfarin.

  4. Melatonin: Taking melatonin with stimulant medications like methylphenidate or amphetamines may increase the risk of sleep disturbances and daytime drowsiness.

  5. MAO inhibitors: Certain supplements, such as St. John’s Wort, ginkgo biloba, and L-tryptophan, should be avoided when taking monoamine oxidase inhibitors (MAOIs), a class of antidepressants sometimes used to treat ADHD, due to the risk of serious interactions.

To minimise the risk of interactions, always inform your healthcare provider about all the supplements and medications you are taking or considering. They can help you identify potential interactions, adjust dosages, or recommend alternative treatments if necessary. Additionally, always start with the lowest effective dose of supplements and monitor for any adverse effects.


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Hemamy, M., Pahlavani, N., Amanollahi, A., Salehi-Abargouei, A., Mottaghi, T., Askari, G., & Hadi, A. (2021). The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial. BMC Pediatrics, 21(1), 178.

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