Bilobalide - A Key Bioactive Component of Ginkgo Biloba
What is Bilobalide?
Bilobalide is a natural compound extracted from the leaves of the Ginkgo biloba tree. It is one of the main active constituents found in standardised Ginkgo biloba extracts along with flavonoids and terpenoids.
Structurally, bilobalide is a sesquiterpene trilactone that gives Ginkgo its many health benefits. It has been shown to protect brain cells and nerves, improve blood flow, act as an antioxidant and anti-inflammatory, and more.
Bilobalide Benefits and Uses
Taking bilobalide supplements offers several evidence-based benefits:
Supports Brain Function
Bilobalide helps protect neurons and nerve tissue from damage due to ageing, stress or other neurological conditions. Research shows it can preserve cognition, memory and concentration whilst supporting learning.
Enhances Blood Flow
By relaxing blood vessels and preventing platelet aggregation, bilobalide enhances circulation and delivery of oxygen and nutrients to bodily tissues. This is especially important for brain, eye, heart and peripheral vascular health.
Acts as an Antioxidant
As a potent antioxidant, bilobalide neutralises free radicals and oxidative stress, which can damage cells. This helps reduce inflammation and protect the body from chronic diseases.
Eases Vertigo Symptoms
Several clinical trials show bilobalide supplements can significantly improve balance, reduce dizziness and ease vertigo linked to inner ear disturbances.
Lowers Risk of Stroke
Some population studies indicate routine intake of bilobalide from Ginkgo extract may lower the long-term risk of stroke. More research is still needed in this area however.
Who May Benefit From Taking Bilobalide?
Bilobalide supplements may benefit the following groups:
- Adults over 50 looking to support healthy brain ageing and circulation.
- Students or professionals seeking to boost memory, cognition and concentration.
- Individuals experiencing occasional anxiety, mild fatigue or headaches.
- People with balance disorders like vertigo or Ménière’s disease.
- Those at higher risk of neurodegenerative disorders like dementia.
- Anyone hoping to reinforce their antioxidant defences through diet.
Always consult a health practitioner before taking bilobalide supplements regularly.
Bilobalide Dosage Guidelines
Most research on bilobalide has used doses between 40-80mg per day. However effects have been observed at 20mg daily.
When choosing a bilobalide supplement in Australia, look for one standardised to at least 3% content to ensure therapeutic potency.
Be sure to follow dosage directions on any bilobalide product and speak to your healthcare provider about a suitable regimen for your individual health status.
Is Bilobalide Safe?
Bilobalide is considered very safe when taken by mouth in appropriate doses. Ginkgo and isolated bilobalide have been extensively studied for their safety profiles.
Side effects are rare but may include mild digestive upset, dizziness, headaches or skin reactions in sensitive individuals.
Bilobalide is not recommended for children or during pregnancy/breastfeeding without medical guidance. Check with your doctor about any interactions with existing herbs or medications.
